Grim Fandango. Manny, Were Art Thou?
There is one thought that constantly saddens me - there is not a chance in the world that there will be another game as good as Grim Fandango. Never ever. Why? Only because an independent developer couldn't pull such a great game and no major video game publisher will agree to finance something like that, seeing that the world is hooked up on the visually stunning games without caring for a solid plot.